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發(fā)布時(shí)間:2018/10/18 來源: 武漢博歐特生物科技有限公司 閱讀次數(shù):356
癌癥通路 - 細(xì)胞凋亡信號(hào)
Apoptosis is the term given to the process of programmed cell death that occurs in muliceiluar orgonisms .Biochemical events lead to characteristic morphological cell changes and death. These changes include cell blebbing, cell shrinkage, nuclear. fragmentation, chromatin condensation, and chromosomal DNA fragmentation. lt is usually advantegeous for a cell to go through apoptosis to assist its progression through a normal life cycle. Apoptosis produces apoptotic bodies which are small celll fragments that phagocytes can engulf and quickly remove before the cell's escaping contents cause toxicty in the surrounding cellular envirorment.
細(xì)胞凋亡是一種發(fā)生在多細(xì)胞生物中的程序性細(xì)胞死亡過程。生物進(jìn)程導(dǎo)致了細(xì)胞形態(tài)特征的改變和死亡。這些變化包括細(xì)胞出泡,細(xì)胞皺縮,核碎裂,染色質(zhì)濃縮和染色體DNA片段化。 對(duì)于細(xì)胞來說,通過細(xì)胞凋亡來幫助其進(jìn)入正常的生命周期通常是有利的。 細(xì)胞凋亡產(chǎn)生凋亡小體,這是小細(xì)胞片段。細(xì)胞逃逸的內(nèi)容物在周圍的細(xì)胞環(huán)境中引起毒性之前,吞噬細(xì)胞可以吞噬并迅速去除它。
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