標(biāo)題PPP2R4 antibody Catalog Number：OM269455

提供者：上海篤瑪生物科技有限公司發(fā)布時間：2024/9/24 閱讀次數(shù)：28次 >>進(jìn)入該公司展臺

Product Name	PPP2R4 antibody
Antibody Type	Primary Antibodies
Product description	Rabbit Polyclonal antibody to PPP2R4 (protein phosphatase 2A activator, regulatory subunit 4)Protein phosphatase 2A is one of the four major Ser/Thr phosphatases ａnd is implicated in the negative control of cell growth ａnd division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, ａnd a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B＇/PR61, ａnd B＇＇/PR72 families. These different regulatory subunits confer distinct enzymatic specificities ａnd intracellular localizations to the holozenzyme. The product of this gene belongs to the B＇ family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] More
Immunogen	Recombinant protein encompassing a sequence within the center region of human PPP2R4. The exact sequence is proprietary.

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	ICC/IFWB
	*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity	Human
Predicted Reactivity	Mouse, Rat, RabbitMouse (96%), Rat (95%), Rabbit (94%)
Concentration	1 mg/ml
Purification	Affinity purified

Gene Synonyms	MGC2184 antibody PP2A antibody PR53 antibody PTPA antibody PPP2R4 antibody PP2A subunit B＇ isoform PR53 antibody phosphotyrosyl phosphatase activator antibody serine/threonine-protein phosphatase 2A activator antibody PP2A phosphatase activator ant More
Molecular Weight(MW)	41 kDa (note) (3)

Application

Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using PPP2R4 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with (Red) at 1:2000.
Application

Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE diluted at 1:1000

Positive Control	A549 , HeLa , HepG2 , HCT116
Application Notes	*Optimal dilutions/concentrations should be determined by the researcher. :

Form	Liquid
Storage Instructions	Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

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