標(biāo)題Anti-ALPL antibody Catalog Number：OM642631

提供者：上海篤瑪生物科技有限公司發(fā)布時(shí)間：2024/9/18 閱讀次數(shù)：22次 >>進(jìn)入該公司展臺(tái)

Gene Symbol	ALPL
Gene Synonyms	HOPS HPPA HPPC HPPI HPPO TNAP TNALP APTNAP TNSALP AP-TNAP TNS-ALP More
Gene Full Name	alkaline phosphatase, biomineralization associated
Gene Summary	This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, ａnd liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue ａnd is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia ａnd skeletal defects. [provided by RefSeq, Oct 2015] More
Molecular Weight(MW)	57 kD(Observed:110 kD）
Cellular Localization	Cell membrane, Membrane, Mitochondrion

WB

Western blot analysis using ALPL antibody against A549(1),Hela (2),A431(3) cell lysate.
ICC/IF

Immunofluorescence analysis of Hela cells using ALPL antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Application Notes	WB:1:200-1:2000 ICC/IF:1:100-1:500

Form	Liquid
Storage Instructions	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide.

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