標題Gab1 (phospho Tyr627) Antibody Catalog Number：OM279348

提供者：上海篤瑪生物科技有限公司發(fā)布時間：2024/9/13 閱讀次數(shù)：27次 >>進入該公司展臺

Product Name	Gab1 (phospho Tyr627) Antibody
Antibody Type	Primary Antibodies
Product description	The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis ａnd plays a central role in cellular growth response, transformation ａnd apoptosis. Two transcript variants encoding different isoforms have been found for this gene.1) Anders Kallin, et al. (2004) J. Biol. Chem ; 279: 17897 - 17904. Hideto Kameda, et al. (2001) Cell Growth Differ ; 12: 307. Masaki Osawa, et al. (2002) J. Cell Biol ; 158: 773. More
Immunogen	Gab1 (Phospho-Tyr627) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 627 (V-E-Y (p) -L-D) derived from Human Gab1.

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	IFWB
	Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:
Species Reactivity	HumanMouse
Concentration	1 mg/ml
Purification	Affinity purified

Gene Symbol	GAB1
Alternative Names	ADDA Growth factor receptor bound protein 2-associated protein 1
Molecular Weight(MW)	110 kDa
Tissue Specificity	This antibody detects endogenous level of Gab1 only when phosphorylated at tyrosine 627.

Entrez Gene	2549
Protein Accession	NP_002030.2

Application

Western blot analysis of lysed extracts from 293 cells untreated or treated with EGF using Gab1 (Phospho-Tyr627).
Application

Immunofluorescence staining of methanol-fixed HeLa cells using Gab1(Phospho-Tyr627).

Application Notes	Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:

Form	Liquid
Storage Instructions	Store antibody at -20˚C for up to one year.
Storage Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.

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