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| 產(chǎn)品描述 | TCO-PEG4-NHS ester is a PROTAC linker bridge belonging to the PEG class.TCO-PEG4-NHS ester can be used to synthesize a wide range of PROTAC molecules.TCO-PEG4-NHS ester is a cleavable ａnd synthetic ADC that can be used in the synthesis of antibody activated molecule conjugates (ADCs). bridge. |
| 體外活性 | PROTACs consist of a pair of dissimilar ligands joined by a linker, where one ligand targets an E3 ubiquitin ligase, ａnd the other ligand targets the specific protein of interest. PROTACs leverage the intracellular ubiquitin-proteasome system to preferentially induce the degradation of target proteins. ADCs are constructed by attaching an ADC cytotoxin to an antibody using an ADC linker.[1] |
| 分子量 | 514.57 |
| 分子式 | C24H38N2O10 |
| CAS No. | 1613439-69-2 |
store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25.73 mg/mL (50 mM), Need ultrasonic
( < 1 mg/mL refers to the product slightly soluble or insoluble )
推送：TCO-PEG4-NHS Ester@2024文獻(xiàn)已更新
| 可選溶劑 | 濃度體積質(zhì)量 | 1 mg | 5 mg | 10 mg | 25 mg |
| DMSO | 1 mM | 1.9434 mL | 9.7169 mL | 19.4337 mL | 48.5843 mL |
| 5 mM | 0.3887 mL | 1.9434 mL | 3.8867 mL | 9.7169 mL | |
| 10 mM | 0.1943 mL | 0.9717 mL | 1.9434 mL | 4.8584 mL | |
| 20 mM | 0.0972 mL | 0.4858 mL | 0.9717 mL | 2.4292 mL | |
| 50 mM | 0.0389 mL | 0.1943 mL | 0.3887 mL | 0.9717 mL |
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